Is the Mechanicum based on '2112'?

It is very possible that the Adeptus Mechanicus of GW's Warhammer 40,000 is inspired by Asimov's Foundation. It is a small book, but well worth the read.

Technology is taught as religion to the uninitiated so that an elite group retain full control. Even the 'high-priests' that are not from the sacred planet are not in on the secret of how to make the machines, but only know what 'ceremonies' to perform to make the machines work.

The Boz said:

Rush can never be before your time. Also, Foundation is a small book, but there are seven of them.

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Well there are actually three books, but more were written afterwards to extend the concept and unite the Robot books. The chapters with relevance to this discussion can all be found in the very first book of the series, which is also the smallest book of the series.