Generally, no. If you play an infantry heavy force, then you can ignore if for the first half of the game. If you use plenty of vehicles, then you'll want to get rid of it fast.
I use two anti-tank squads with missile launchers and one with autocannons. I tend to use the autocannons against Skimmers, and the missile launchers against wraithlords and avatars. Usually, if the wraithlord is not in cover, I can kill one a turn with 6 missile launchers if my dice are friendly, or in two turns if they are not. I don't waste tank firepower on wraithlords, or any other multiwound monstrous creature.