You want crazy? The Inquisitorial Representative sitting on the High Lords of Terra, along with many influential Inquisitor-Lords and Grandmasters (Caidin, etc.) are in fact Squats. It explains how they disappeared.
"You do not need to look to the stars to find the greatest obstacle this Conclave faces, my brothers. Simply gaze around this room and you will find such a sea of discord as to make your foes cackle with glee." - Inquisitor Eistus Gracker in address to the Calixian Conclave
"There are dark pitted corners of our universe that have bred the most unfathomable horrors and blasphemies that would burn and blind the sanest man. Fortunately sanity has never been a prerequisite of membership in the Holy Ordos." - Inquisitor Silas Marr