Well Kor Phaeron, Luther, and a bunch of other prominent figures in the Legions were humans with a couple of extra organs thrown in to make them into pseudo-Astartes, and they did well enough for themselves. I don't see why there couldn't be a distant Mechanicus outpost or something that still has the tech to do it in 40k.

Excuse my language but what the hell is a pseudo-Astartes?

Bad ass humans with shinny, spinny chrome rims. Basically humans who went through intense augmentation processes that gave them physical abilities comparable to those of full marines. They were usually very important people who were to old to undergo the same process that marines did.

What's the process on making them? I dbout IG player was going for the pseudo-Astartes process.

No clue, but it was reserved for the best of the best and only when needed, so even if they could do it in M41, they wouldn't be doing it for anyone short of a saint or something similar.

"A few companies of the Lostock 23rd were modified by the techpriests to fight in this hellish war zone, incorporating many organs and drug secreting glands that enabled them to survive unprotected, as well as boosting their combat abilities and aggressiveness."

From the entry for Sgt Stone, Inquisitor rule book, page 111.

Thank you gen.ahab. I think from the OP, the IG wouldnt' have the resources wasted on them. Flesh stock is cheap, technology is expensive in knowledge and resources. Just throw another million or two IG at the problem, but save the fancy implants/armor/weapons for the Astares.

From a logistics standpoint, considering how the Imperium uses the IG in battle, all those implants would likely only get them a couple more days life in the meatgrinder. As well, considering these aren't PDF, all those implants and resources are only going to be sent offworld. I think a planetary economy and the Imperial Army would be more concerned with generating additional IG Regiments than overjuicing what is there.

See my previous post. If the situation warrants it IG units will get the upgrades. It's also been shown that the IG have messed with breeding genetic super soldiers, as seen in the Last Chancers books. I'm sure that would be a huge investment in time and resources, but they did it any way.

Couple of things.

The Gland War Veterans are/were 1 regiment, with a few companies, and they did not have as much modification as the person's fluff, they said double/sm(low grade) organs everywhere. The Gland Vets also only had modifications to allow them to not keel over when they went outside the factory complexes.

The Afriel Strain were low numbers (500 from Mach), they couldn't make up a regiment.

EDIT: Doing a bit more reading there are 'a few regiments of gland war veterans can be found through out the galaxy'

They had more than just lung modifications, they also had modifications that boosted aggression and combat skills. Presumably that would mean adrenal system and mental and reflexive acuity upgrades, beyond just stim injectors.