Yep, I use loads of DoW mods.
There's True Warhammer, which has limited requisition that works exactly as points, though weapon balance is awful.
Then there's DoW Pro, which is quite a lot like the normal game but with small changes.
Firestorm Over Kronos is probably the best that isn't radically different, without anything strange like completely different damage rates or differently done resources. The god choosing of the Chaos forces is really excellent.
The table-top round up mod is probably my favourite. Weapon damage is boosted to levels more like table-top, and units are far better scaled to buildings and vehicles. No more guardsmen as big as their bunkers! However slow CC units die before doing anything, long range units rule over everything, and blast things like orbital strikes, the skyray missiles, strafing runs etc kill EVERYTHING they hit. I've lost most of my army to them many times, and it gets frustrating. Also for DC they implimated a stupid limited research thing. Problem is to specify in some things only one or two upgrades help, and to specialise in others you need more than the possible amount.
I also like playing race mods, like the good tyranid one.